{"id":29711,"date":"2024-11-13T16:24:00","date_gmt":"2024-11-13T20:24:00","guid":{"rendered":"https:\/\/fusfoundation-redesign.storywaredev.com\/?post_type=sw_disease_condition&#038;p=29711"},"modified":"2026-05-13T18:18:19","modified_gmt":"2026-05-13T22:18:19","slug":"equine-sarcoid","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/equine-sarcoid\/","title":{"rendered":"Equine Sarcoid"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-focused-ultrasound-therapy-nbsp\">Focused Ultrasound Therapy&nbsp;<\/h2>\n\n\n\n<p>Focused ultrasound is a rapidly evolving, therapeutic technology that could transform the quality of life and decrease the cost of care for horses that have developed equine sarcoid. These predominantly benign, lesions can take a variety of forms, ranging from scaling and crusting with variable alopecia to (less frequently) lumps or tumor like masses. They can be disabling for horses, as they can frequently involve the eyes, ears and girth regions. Bovine papillomavirus is important in its etiology. This novel technology focuses beams of ultrasound energy precisely and accurately on targets in the body without damaging surrounding normal tissue.&nbsp;<\/p>\n\n\n\n<p><strong>How it Works<\/strong>&nbsp;<\/p>\n\n\n\n<p>Focused ultrasound will use the mechanical effect of histotripsy to disrupt the physical structure of the targeted equine sarcoid. This effort will be done in several different doses, and there will be immunotherapeutic biomarkers captured that will be contrasted with non-histotripsy level.&nbsp;&nbsp;<\/p>\n\n\n\n<p>The primary options for treatment of equine sarcoid includes medication and possibly chemotherapy, but the recurrent nature of these lesions makes this an unmet need for horse owners.&nbsp;&nbsp;<\/p>\n\n\n\n<p>For certain patients, focused ultrasound could provide a more effective alternative to the limited conventional options that currently exist. While significant work has been accomplished, there is still much to be done before this technology will be widely available.&nbsp;<\/p>\n\n\n\n<p><strong>Advantages<\/strong>&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Focused ultrasound is non-invasive, so it does not carry added concerns like surgical wound healing or infection.&nbsp;&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Focused ultrasound can reach the desired target without damaging surrounding tissue.&nbsp;<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li>It can be repeated, if necessary.&nbsp;<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-clinical-trials-nbsp\">Clinical Trials&nbsp;<\/h2>\n\n\n\n<p>This therapy is currently only seen in horses. There is an active <a href=https://www.fusfoundation.org/"https:////research.vetmed.vt.edu//clinical-trials.html/" target=\"_blank\" rel=\"noreferrer noopener\" class=\"ek-link\"><strong>clinical trial<\/strong><\/a> operating at Virginia Tech.&nbsp;&nbsp;&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-regulatory-approval-and-reimbursement-nbsp-nbsp\">Regulatory Approval and Reimbursement&nbsp;&nbsp;<\/h2>\n\n\n\n<p>Focused ultrasound treatment for equine sarcoid is not yet approved by regulatory bodies or covered by medical (horse) insurance companies.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-notable-papers-nbsp\">Notable Papers&nbsp;<\/h2>\n\n\n\n<p>Ellero\u00a0N, Maggi A, Busoni V,\u00a0Imposimato\u00a0I, Castagnetti C, Lanci A, Mariella J,\u00a0Freccero\u00a0F.\u00a0<a href=https://www.fusfoundation.org/"https:////pubmed.ncbi.nlm.nih.gov//41461358///" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Development and application of a focused ultrasound protocol in neonatal foals<\/strong><\/a>. Vet J. 2026\u00a0Feb;315:106543.\u00a0doi: 10.1016\/j.tvjl.2025.106543.\u00a0Epub\u00a02025 Dec 27. PMID: 41461358\u00a0<\/p>\n\n\n\n<p>Haspeslagh M, Vlaminck LE, Martens AM. <a class=\"ek-link\" href=https://www.fusfoundation.org/"https:////pubmed.ncbi.nlm.nih.gov//27439349///" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Treatment\u202fof\u202fsarcoids\u202fin\u202fequids: 230 cases (2008-2013)<\/strong><\/a>. J Am Vet Med Assoc. 2016 Aug 1;249(3):311-8. doi: 10.2460\/javma.249.3.311. PMID:\u202f27439349\u202f&nbsp;<\/p>\n\n\n\n<p>Staiger EA, Tseng CT, Miller D, Cassano JM, Nasir L, Garrick D, Brooks SA, Antczak DF. <a class=\"ek-link\" href=https://www.fusfoundation.org/"https:////pubmed.ncbi.nlm.nih.gov//27037728///" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Host\u202fgenetic\u202finfluence\u202fon\u202fpapillomavirus-induced tumors in the\u202fhorse<\/strong><\/a>. Int J Cancer. 2016 Aug 15;139(4):784-92. doi: 10.1002\/ijc.30120. Epub 2016 May 6. PMID:\u202f27037728&nbsp;<\/p>\n\n\n\n<p><em><strong>Click<\/strong> <a class=\"ek-link\" href=https://www.fusfoundation.org/"https:////pubmed.ncbi.nlm.nih.gov//?term=Treatment+of+Sarcoids+in+equids&amp;sort=date\%22 target=\"_blank\" rel=\"noreferrer noopener\"><strong>here<\/strong><\/a><strong> for additional references from PubMed.&nbsp;&nbsp;<\/strong>&nbsp;<\/em><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[29],"sw_disease_condition_stage":[20],"class_list":["post-29711","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-miscellaneous"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Equine Sarcoid - Focused Ultrasound Foundation<\/title>\n<!-- Added by HTTrack --><meta http-equiv="content-type" content="text/html;charset=utf-8" /><!-- /Added by HTTrack -->
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