{"id":201,"date":"2021-12-08T18:04:00","date_gmt":"2021-12-08T18:04:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=201"},"modified":"2025-04-10T11:48:01","modified_gmt":"2025-04-10T15:48:01","slug":"cardiac-pacing","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-pacing\/","title":{"rendered":"Cardiac Pacing"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients who have myocardial electrical dysfunction, and therefore need cardiac pacing. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body without damaging surrounding normal tissue.<\/p>\n\n\n\n

How it Works<\/strong>
Targeting the left ventricle and septum with focused ultrasound will cause myocardial contractions. This technique has been demonstrated in both small and large animals, indicating that perhaps future pacing may be accomplished noninvasively with focused ultrasound.<\/p>\n\n\n\n

Advantages<\/strong>
The primary options for treatment of myocardial electrical dysfunction include medication and\/or invasive procedures.<\/p>\n\n\n\n

For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications \u2013 such as surgical wound healing or infection \u2013 at a lower cost. Focused ultrasound can also reach the desired target without damaging surrounding tissue, and it can be repeated, if necessary.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

At the present time, there are no clinical trials recruiting patients for focused ultrasound cardiac pacing.<\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>.\u00a0<\/p>\n\n\n\n

Regulatory Approval and Reimbursement<\/h2>\n\n\n\n

Focused ultrasound treatment for cardiac pacing is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Yao Y, Qian J, Rong S, Huang Y, Xiong B, Yang G, Zhang D, Deng S, Tan J, Zhu Q, Deng C, Liu D, Ran H, Wang Z, Huang J.\u00a0Cardiac Denervation for Arrhythmia Treatment with Transesophageal Ultrasonic Strategy in Canine Models<\/strong><\/a>. Ultrasound Med Biol. 2019 Feb;45(2):490-499. doi: 10.1016\/j.ultrasmedbio.2018.10.013. Epub 2018 Dec 6.<\/p>\n\n\n\n

Jang KW, Tu TW, Nagle ME, Lewis BK, Burks SR, Frank JA.\u00a0Molecular and histological effects of MR-guided pulsed focused ultrasound to the rat heart<\/strong><\/a>. J Transl Med. 2017 Dec 13;15(1):252. doi: 10.1186\/s12967-017-1361-y.<\/p>\n\n\n\n

Fabrice Marquet, Pierre Bour, Fanny Vaillant, Sana Amraoui, R\u00e9mi Dubois, Philippe Ritter, Michel Ha\u00efssaguerre, M\u00e9l\u00e8ze Hocini, Olivier Bernus, and Bruno Quesson. Non-invasive cardiac pacing with image-guided focused ultrasound<\/strong><\/a>. Published online 2016 Nov 9. doi: 10.1038\/srep36534

Reyes G, Ruyra X, Valderrama F, Jimenez A, Duran D, Perez E, Daroca T, Moya J, Ramirez U, Aldamiz G.\u00a0High intensity focused ultrasound ablation for atrial fibrillation: results from the National Spanish Registry<\/strong><\/a>. Minerva Cardioangiol. 2016 Oct;64(5):501-6.

Kohut AR, Vecchio C, Adam D, Lewin PA.\u00a0The potential of ultrasound in cardiac pacing and rhythm modulation<\/strong><\/a>. Expert Rev Med Devices. 2016 Sep;13(9):815-22. doi: 10.1080\/17434440.2016.1217772.

Livneh A, Kimmel E, Kohut AR, Adam D.\u00a0Extracorporeal acute cardiac pacing by high intensity focused ultrasound<\/strong><\/a>. Prog Biophys Mol Biol. 2014 Aug;115(2-3):140-53. doi: 10.1016\/j.pbiomolbio.2014.08.007.<\/p>\n\n\n\n

Click here<\/a>\u00a0for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[5],"sw_disease_condition_stage":[14],"class_list":["post-201","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-cardiovascular"],"acf":[],"yoast_head":"\nCardiac Pacing - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Pacing\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-pacing\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cardiac Pacing - 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