{"id":2795,"date":"2021-12-08T20:02:00","date_gmt":"2021-12-08T20:02:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=2795"},"modified":"2025-04-10T11:46:11","modified_gmt":"2025-04-10T15:46:11","slug":"cardiac-hypertrophy","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/","title":{"rendered":"Cardiac Hypertrophy"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with cardiac hypertrophy. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the heart without damaging surrounding normal tissue.<\/p>\n\n\n\n

How it Works<\/strong>
The mechanism of action is to use low-intensity focused ultrasound to induce intravenous nanoparticles to release therapeutics only in the heart, enabling precise therapeutic benefit without systemic toxicity. This novel technique has been demonstrated<\/strong><\/a> using a preclinical model but has not yet been translated to the clinic. <\/p>\n\n\n\n

Advantages<\/strong>
The primary options for treatment of cardiac hypertrophy include lifestyle choices and medications, which frequently have limitations due to side effects. Surgical removal of cardiac hypertrophy has been considered and is still experimental.\u202f<\/p>\n\n\n\n

For certain patients, focused ultrasound could provide a noninvasive treatment for cardiac hypertrophy that could have less risk of complications \u2013 such as\u202fsurgical wound healing or infection \u2013 at a lower cost.\u202fIt can reach the desired target without damaging surrounding tissue and is repeatable, if necessary. Focused ultrasound may also be able to offer treatment for cardiac hypertrophy without the adverse side effects of current medications.\u202f<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment of cardiac hypertrophy.<\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>.\u00a0<\/p>\n\n\n\n

Regulatory Approval and Reimbursement <\/h2>\n\n\n\n

Focused ultrasound treatment for cardiac hypertrophy is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Anghel L, St\u0103tescu C, \u0218erban IL, M\u0103r\u0103nduc\u0103 MA, Butcovan D, Clement A, Bostan M, Sasc\u0103u R.\u00a0The Advantages of New Multimodality Imaging in Choosing the Optimal Management Strategy for Patients with Hypertrophic Cardiomyopathy<\/strong><\/a>. Diagnostics (Basel). 2020 Sep 19;10(9):E719. doi: 10.3390\/diagnostics10090719.<\/p>\n\n\n\n

Zhou Q, Zeng Y, Xiong Q, Zhong S, Li P, Ran H, Yin Y, Reutelingsperger C, Prinze FW, Ling Z.\u00a0Nanoagents for Low-Intensity Focused Ultrasound-Triggered Ultrasound Molecular Imaging of Myocardial Fibrosis in Rabbits<\/strong><\/a>. ACS Appl Mater Interfaces. 2019 Jul 3;11(26):23006-23017. doi: 10.1021\/acsami.9b05999. Epub 2019 Jun 24.

Rothman A, Jonas M, Castel D, Tzafriri AR, Traxler H, Shav D, Leon MB, Ben-Yehuda O, Rubin L.\u00a0Pulmonary Artery Denervation Using Catheter based Ultrasonic Energy<\/strong><\/a>. EuroIntervention. 2019 May 7. pii: EIJ-D-18-01082. doi: 10.4244\/EIJ-D-18-01082.<\/p>\n\n\n\n

Zhao X, Luo W, Hu J, Zuo L, Wang J, Hu R, Wang B, Xu L, Li J, Wu M, Li P, Liu L.\u00a0Cardiomyocyte-targeted and 17\u03b2-estradiol-loaded acoustic nanoprobes as a theranostic platform for cardiac hypertrophy<\/strong><\/a>. J Nanobiotechnology. 2018 Mar 30;16(1):36. doi: 10.1186\/s12951-018-0360-3.

Click here<\/a>\u00a0for additional references from PubMed.<\/strong><\/em><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":2,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[5],"sw_disease_condition_stage":[14],"class_list":["post-2795","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-cardiovascular"],"acf":[],"yoast_head":"\nCardiac Hypertrophy - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Hypertrophy\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cardiac Hypertrophy - Focused Ultrasound Foundation\" \/>\n<meta property=\"og:description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Hypertrophy\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/\" \/>\n<meta property=\"og:site_name\" content=\"Focused Ultrasound Foundation\" \/>\n<meta property=\"article:modified_time\" content=\"2025-04-10T15:46:11+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/\",\"url\":\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/\",\"name\":\"Cardiac Hypertrophy - Focused Ultrasound Foundation\",\"isPartOf\":{\"@id\":\"https:\/\/www.fusfoundation.org\/#website\"},\"datePublished\":\"2021-12-08T20:02:00+00:00\",\"dateModified\":\"2025-04-10T15:46:11+00:00\",\"description\":\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Hypertrophy\",\"breadcrumb\":{\"@id\":\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.fusfoundation.org\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cardiac Hypertrophy\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.fusfoundation.org\/#website\",\"url\":\"https:\/\/www.fusfoundation.org\/\",\"name\":\"Focused Ultrasound Foundation\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.fusfoundation.org\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.fusfoundation.org\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.fusfoundation.org\/#organization\",\"name\":\"Focused Ultrasound Foundation\",\"url\":\"https:\/\/www.fusfoundation.org\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.fusfoundation.org\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/cdn.fusfoundation.org\/2023\/08\/24140306\/focused-ultrasound-foundation-logo.png\",\"contentUrl\":\"https:\/\/cdn.fusfoundation.org\/2023\/08\/24140306\/focused-ultrasound-foundation-logo.png\",\"width\":730,\"height\":76,\"caption\":\"Focused Ultrasound Foundation\"},\"image\":{\"@id\":\"https:\/\/www.fusfoundation.org\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Cardiac Hypertrophy - Focused Ultrasound Foundation","description":"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Hypertrophy","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/","og_locale":"en_US","og_type":"article","og_title":"Cardiac Hypertrophy - Focused Ultrasound Foundation","og_description":"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Hypertrophy","og_url":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/","og_site_name":"Focused Ultrasound Foundation","article_modified_time":"2025-04-10T15:46:11+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/","url":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/","name":"Cardiac Hypertrophy - Focused Ultrasound Foundation","isPartOf":{"@id":"https:\/\/www.fusfoundation.org\/#website"},"datePublished":"2021-12-08T20:02:00+00:00","dateModified":"2025-04-10T15:46:11+00:00","description":"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Cardiac Hypertrophy","breadcrumb":{"@id":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/cardiac-hypertrophy\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.fusfoundation.org\/"},{"@type":"ListItem","position":2,"name":"Cardiac Hypertrophy"}]},{"@type":"WebSite","@id":"https:\/\/www.fusfoundation.org\/#website","url":"https:\/\/www.fusfoundation.org\/","name":"Focused Ultrasound Foundation","description":"","publisher":{"@id":"https:\/\/www.fusfoundation.org\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.fusfoundation.org\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.fusfoundation.org\/#organization","name":"Focused Ultrasound Foundation","url":"https:\/\/www.fusfoundation.org\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.fusfoundation.org\/#\/schema\/logo\/image\/","url":"https:\/\/cdn.fusfoundation.org\/2023\/08\/24140306\/focused-ultrasound-foundation-logo.png","contentUrl":"https:\/\/cdn.fusfoundation.org\/2023\/08\/24140306\/focused-ultrasound-foundation-logo.png","width":730,"height":76,"caption":"Focused Ultrasound Foundation"},"image":{"@id":"https:\/\/www.fusfoundation.org\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/sw_disease_condition\/2795","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/sw_disease_condition"}],"about":[{"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/types\/sw_disease_condition"}],"version-history":[{"count":3,"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/sw_disease_condition\/2795\/revisions"}],"predecessor-version":[{"id":34078,"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/sw_disease_condition\/2795\/revisions\/34078"}],"wp:attachment":[{"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/media?parent=2795"}],"wp:term":[{"taxonomy":"sw_disease_condition_cat","embeddable":true,"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/sw_disease_condition_cat?post=2795"},{"taxonomy":"sw_disease_condition_stage","embeddable":true,"href":"https:\/\/www.fusfoundation.org\/wp-json\/wp\/v2\/sw_disease_condition_stage?post=2795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}