{"id":2867,"date":"2021-12-08T20:26:00","date_gmt":"2021-12-09T00:26:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&#038;p=2867"},"modified":"2025-09-04T15:09:16","modified_gmt":"2025-09-04T19:09:16","slug":"esophageal-cancer","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/esophageal-cancer\/","title":{"rendered":"Esophageal Cancer"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-focused-ultrasound-therapy\">Focused Ultrasound Therapy<\/h2>\n\n\n\n<p>Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with tumors of the esophagus. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body without damaging surrounding normal tissue.<\/p>\n\n\n\n<p><strong>How it Works<\/strong><br>Where the beams converge, focused ultrasound produces several therapeutic effects that are being evaluated. One mechanism is the production of precise ablation (thermal destruction of tissue) with the goal of either completely or partially destroying the tumor tissue. Partial treatment is believed to stimulate the patient\u2019s immune response, which may have a broader impact. Another mechanism of action is to pre-treat the tumor with pulsed focused ultrasound which may enable improved therapeutic absorption.<\/p>\n\n\n\n<p><strong>Advantages<\/strong><br>The primary option for treatment of esophageal tumors is invasive surgery, although radiation, chemotherapy or other pharmaceuticals may also be used.<\/p>\n\n\n\n<p>For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications \u2013&nbsp;like surgical wound healing or infection \u2013 at a lower cost.&nbsp;Focused ultrasound can reach the desired target without damaging surrounding tissue, and it could also enhance the chemotherapy dose for the target, with less impact to the rest of the patient. It can also be repeated, if necessary.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-clinical-trials\">Clinical Trials<\/h2>\n\n\n\n<p>At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment of esophageal cancer.<\/p>\n\n\n\n<p>The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click <a href=\"https:\/\/clinicaltrials.gov\/search?cond=Esophageal%20Cancer&amp;term=focused%20ultrasound&amp;aggFilters=status:not%20rec\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>here<\/strong><\/a>, it will take you to the latest information available from <a href=\"https:\/\/www.clinicaltrials.gov\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-regulatory-approval-and-reimbursement\">Regulatory Approval and Reimbursement<\/h2>\n\n\n\n<p>Focused ultrasound treatment for head and neck tumors is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-notable-papers\">Notable Papers<\/h2>\n\n\n\n<p>Palmeri ML, Frinkley KD, Zhai L, Gottfried M, Bentley RC, Ludwig K, Nightingale KR.\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/16231837\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Acoustic radiation force impulse (ARFI) imaging of the gastrointestinal tract<\/strong><\/a>. Ultrason Imaging. 2005 Apr;27(2):75-88. doi: 10.1177\/016173460502700202.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=(%22focused%20ultrasound%22%20OR%20HIFU)%20and%20%22esophageal%22&amp;sort=date\" target=\"_blank\" rel=\"noreferrer noopener\">Click here<\/a> for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[21,26],"sw_disease_condition_stage":[20],"class_list":["post-2867","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-gastrointestinal","sw_disease_condition_cat-oncological"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - 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