{"id":2933,"date":"2021-12-08T20:37:00","date_gmt":"2021-12-08T20:37:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=2933"},"modified":"2025-04-15T10:09:36","modified_gmt":"2025-04-15T14:09:36","slug":"muscle-atrophy","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/muscle-atrophy\/","title":{"rendered":"Muscle Atrophy"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with muscle atrophy. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body.<\/p>\n\n\n\n

How it Works<\/strong>
Where the beams converge, pulsed focused ultrasound generates non-thermal stimulation of angiogenesis on satellite cells. In the preclinical research setting of decreased muscle use, this treatment yielded diminished muscle atrophy compared to controls. While this result is encouraging, more work is needed before this technique can move toward clinical application.<\/p>\n\n\n\n

Advantages<\/strong>
The primary options for treatment of muscle atrophy are dependent on the perceived cause and can include invasive surgery.<\/p>\n\n\n\n

For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications \u2013 such as surgical wound healing or infection \u2013 at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment of muscle atrophy.<\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>.\u00a0<\/p>\n\n\n\n

Regulatory Approval and Reimbursement<\/h2>\n\n\n\n

Focused ultrasound treatment for muscle atrophy is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Matsumoto Y, Nakano J, Oga S, Kataoka H, Honda Y, Sakamoto J, Okita M. The non-thermal effects of pulsed ultrasound irradiation on the development of disuse muscle atrophy in rat gastrocnemius muscle. <\/a>Ultrasound Med Biol. 2014

Okita M, Nakano J, Kataoka H, Sakamoto J, Origuchi T, Yoshimura T. Effects of therapeutic ultrasound on joint mobility and collagen fibril arrangement in the endomysium of immobilized rat soleus muscle.<\/a> Ultrasound Med Biol. 2009 Feb;35(2):237-44.<\/p>\n\n\n\n

W. J. Tyler, Y. Tufail, M. Finsterwald, M. L. Tauchmann, E. J. Olson, and C. Majestic, \u201cRemote excitation of neuronal circuits using low-intensity, low-frequency ultrasound<\/a>.,\u201d PLoS ONE, vol. 3, no. 10, Oct. 2008.<\/p>\n\n\n\n

Click here<\/a>\u00a0for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[25],"sw_disease_condition_stage":[14],"class_list":["post-2933","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-pain-relief"],"acf":[],"yoast_head":"\nMuscle Atrophy - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Muscle Atrophy\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/muscle-atrophy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Muscle Atrophy - 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