{"id":2951,"date":"2021-12-08T20:41:00","date_gmt":"2021-12-08T20:41:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&#038;p=2951"},"modified":"2025-04-16T10:29:00","modified_gmt":"2025-04-16T14:29:00","slug":"sacral-chordomas","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/sacral-chordomas\/","title":{"rendered":"Sacral Chordomas"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\" id=\"h-focused-ultrasound-therapy\">Focused Ultrasound Therapy<\/h2>\n\n\n\n<p>Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with sacral chordomas. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the body without damaging surrounding normal tissue.<\/p>\n\n\n\n<p><strong>How it Works<\/strong><br>Where the beams converge, focused ultrasound produces precise ablation (thermal destruction of tissue) enabling sacral chordomas to be treated without surgery.<\/p>\n\n\n\n<p>Focused ultrasound has been used to&nbsp;<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27936948\" target=\"_blank\" rel=\"noreferrer noopener\">treat four patients<\/a>&nbsp;with sacral chordomas in England with encouraging results. The researchers report tumor volume was reduced over time in three patients for whom follow up scans were available. Tumor necrosis was documented in two out of the three patients.<\/p>\n\n\n\n<p><strong>Advantages<\/strong><br>The primary options for treatment of sacral chordomas include invasive surgery.<\/p>\n\n\n\n<p>For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications \u2013 such as surgical wound healing or infection \u2013 at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary. This is particularly important as even with best efforts, chodomas can seed the surgical wound and recur.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-clinical-trials\">Clinical Trials<\/h2>\n\n\n\n<p>There are no clinical trials treating sacral chordoma that we are aware of currently.<\/p>\n\n\n\n<p>The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click <a href=\"https:\/\/clinicaltrials.gov\/search?cond=Chordoma&amp;term=focused%20ultrasound&amp;aggFilters=status:not%20rec\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>here<\/strong><\/a>, it will take you to the latest information available from <a href=\"https:\/\/www.clinicaltrials.gov\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-regulatory-approval-and-reimbursement-nbsp\">Regulatory Approval and Reimbursement&nbsp;<\/h2>\n\n\n\n<p>Focused ultrasound treatment for sacral chordoma is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-patient-advocacy-nbsp\">Patient Advocacy&nbsp;<\/h2>\n\n\n\n<p><a href=\"https:\/\/www.chordomafoundation.org\/\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>The Chordoma Foundation<\/strong><\/a>\u00a0is a nonprofit organization working to improve the lives of those affected by chordoma and lead the search for a cure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"h-notable-papers\">Notable Papers<\/h2>\n\n\n\n<p>Chetan MR, Lyon PC, Wu F, Phillips R, Cranston D, Gillies MJ, Bojanic S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31428215\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>Role of diffusion-weighted imaging in monitoring treatment response following high-intensity focused ultrasound ablation of recurrent sacral chordoma<\/strong><\/a>. Radiol Case Rep. 2019 Aug 1;14(10):1197-1201. doi: 10.1016\/j.radcr.2019.07.004. eCollection 2019 Oct.<\/p>\n\n\n\n<p>Gillies MJ, Lyon PC, Wu F, Leslie T, Chung DY, Gleeson F, Cranston D, Bojanic S.\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27936948\" target=\"_blank\" rel=\"noreferrer noopener\"><strong>High-intensity focused ultrasonic ablation of sacral chordoma is feasible: a series of four cases and details of a national clinical trial<\/strong><\/a>. Br J Neurosurg. 2016 Dec 12:1-6.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=(%22focused+ultrasound%22+OR+HIFU)+and+%22chordoma%22\" target=\"_blank\" rel=\"noreferrer noopener\">Click here<\/a>\u00a0for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":1,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[25,26],"sw_disease_condition_stage":[20],"class_list":["post-2951","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-pain-relief","sw_disease_condition_cat-oncological"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - 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