{"id":2954,"date":"2021-12-08T20:41:00","date_gmt":"2021-12-09T00:41:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=2954"},"modified":"2026-05-13T18:46:47","modified_gmt":"2026-05-13T22:46:47","slug":"sacroiliitis","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/sacroiliitis\/","title":{"rendered":"Sacroiliitis"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/strong><\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with sacroiliitis. This novel technology focuses beams of ultrasound energy precisely and accurately on targets in the body without damaging surrounding normal tissue. <\/p>\n\n\n\n

How it Works
<\/strong>Where the beams converge, the ultrasound produces precise ablation of nerve tissue that supplies the inflamed sacroiliac joints, alleviating the pain caused by sacroiliitis.<\/p>\n\n\n\n

Advantages<\/strong>
The primary options for treatment of sacroiliitis include medication (both over the counter and prescription pain relievers), physical therapy, joint injections, radiofrequency ablation (RFA) and invasive surgery.

For certain patients, focused ultrasound could provide a noninvasive alternative to RFA or surgery with less risk of complications \u2013 such as surgical wound healing or infection \u2013 at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

A clinical trial<\/strong><\/a> is in the final stages of organization at UVA for the treatment of sacroiliac arthritis.  <\/p>\n\n\n\n

A clinical trial<\/strong><\/a> using focused ultrasound to treat patients with sacroiliitis has begun in Israel. <\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>. <\/p>\n\n\n\n

Regulatory Approvals and Reimbursement<\/h2>\n\n\n\n

Focused ultrasound treatment for sacroiliitis is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Gur R, Harel T, Kelmer P, Sheinfeld R, Jacobi O, Goor-Aryeh I, Ungar L. First Treatment of a Sacroiliitis Patient Using Fluoroscopy Guided High Intensity Focused Ultrasound for Sacroiliitis<\/strong><\/a>. Pain\u00a0Pract. 2026 Apr;26(4):e70134.\u00a0doi: 10.1111\/papr.70134. PMID: 41814391\u00a0<\/p>\n\n\n\n

Gao G, Thomas Z, Kantarci H, Pacharinsak C, Zuchero JB, Pauly KB, Yeomans DC, Anderson TA. Focused Ultrasound-Induced Peripheral Nerve Blockade: Duration of Changes to Thermal Withdrawal Latency and Nerve Structure After Focused Ultrasound Application to the Sciatic Nerve in a Rat Model of Acute Pain<\/strong><\/a>. J Neurosci Res. 2025 Sep;103(9):e70079. doi: 10.1002\/jnr.70079. PMID: 40990106 <\/p>\n\n\n\n

Najafi A., Sartoretti E., Binkert CA. Sacroiliac Joint Ablation Using MR-HIFU<\/a><\/strong>. Cardiovasc Intervent Radiol (2019) 42:1363\u20131365<\/p>\n\n\n\n

Kaye EA, Maybody M, Monette S, Solomon SB, Gulati A. Ablation of the sacroiliac joint using MR-guided high intensity focused ultrasound: a preliminary experiment in a swine model<\/strong><\/a>. J Ther Ultrasound. 2017 Jun 26;5:17. doi: 10.1186\/s40349-017-0095-x.<\/p>\n\n\n\n

Scipione R, Anzidei M, Bazzocchi A, Gagliardo C, Catalano C, Napoli A. HIFU for Bone Metastases and other Musculoskeletal Applications<\/strong><\/a>. Semin Intervent Radiol. 2018 Oct;35(4):261-267. doi: 10.1055\/s-0038-1673363. Epub 2018 Nov 5. Review.<\/p>\n\n\n\n

Kaye EA, Monette S, Srimathveeravalli G, Maybody M, Solomon SB, Gulati A. MRI-guided focused ultrasound ablation of lumbar medial branch nerve: Feasibility and safety study in a swine model<\/strong><\/a>. Int J Hyperthermia. 2016 Nov;32(7):786-94. doi: 10.1080\/02656736.2016.1197972. Epub 2016 Jul 21.<\/p>\n\n\n\n

Click here<\/a> for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[25],"sw_disease_condition_stage":[20],"class_list":["post-2954","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-pain-relief"],"acf":[],"yoast_head":"\nSacroiliitis - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn about clinical trials that are investigating the use of focused ultrasound to treat Sacroiliitis\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/sacroiliitis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sacroiliitis - 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