{"id":3016,"date":"2021-12-08T13:43:00","date_gmt":"2021-12-08T13:43:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=3016"},"modified":"2025-07-17T11:12:52","modified_gmt":"2025-07-17T15:12:52","slug":"hydrocephalus","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/hydrocephalus\/","title":{"rendered":"Hydrocephalus\u00a0"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with hydrocephalus. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the brain without damaging surrounding normal tissue.<\/p>\n\n\n\n

How it Works<\/strong>
Where the beams converge, focused ultrasound produces precise ablation (thermal destruction of tissue) that creates one or more openings. These openings allow the cerebrospinal fluid (CSF) that is contained in the cavity to pass through the holes, resulting the CSF to circulate and be reabsorbed by the arachnoid villi. While early results are promising, there is still much to be done before this technology will be available clinically.<\/p>\n\n\n\n

Advantages<\/strong>
The primary options for treatment of hydrocephalus includes invasive surgery.<\/p>\n\n\n\n

For certain patients, focused ultrasound could provide a noninvasive alternative to surgery. It is noninvasive, so it does not carry added concerns like surgical wound healing or infection. Focused ultrasound can reach the desired target without damaging surrounding tissue, and it can be repeated, if necessary.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

At the present time, there are no clinical trials recruiting patients for focused treatment of hydrocephalus.<\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>. <\/p>\n\n\n\n

Regulatory Approval and Reimbursement<\/h2>\n\n\n\n

Focused ultrasound treatment for hydrocephalus is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Dhawan SS, Hacein-Bey L, Massoud TF. Choroid plexus enlargement in idiopathic normal pressure hydrocephalus and concept proposal for noninvasive volume-reductive therapies<\/strong><\/a>. Brain Res. 2025 Jun 15;1857:149593. doi: 10.1016\/j.brainres.2025.149593. Epub 2025 Mar 27. PMID: 40157411\u00a0<\/p>\n\n\n\n

Gomez-Gonzalez E, Munoz-Gonzalez FJ, Barriga-Rivera A, Perales-Esteve MA, Guerrero-Claro M, Fernandez-Lizaranzu I, Requena-Lancharro D, Rosales-Martinez M, Marquez-Rivas J. Contactless Ultrasonic Cavitation for the Prevention of Shunt Obstruction in Hydrocephalus: A Proof-of-Concept Study<\/a><\/strong>. Oper Neurosurg (Hagerstown). 2022 Nov 1;23(5):420-426. doi: 10.1227\/ons.0000000000000372. Epub 2022 Sep 19. <\/p>\n\n\n\n

Yang AI, Chaibainou H, Wang S, Hitti FL, McShane BJ, Tilden D, Korn M, Blanke A, Dayan M, Wolf RL, Baltuch GH. Focused Ultrasound Thalamotomy for Essential Tremor in the Setting of a Ventricular Shunt: Technical Report<\/strong><\/a>. Oper Neurosurg (Hagerstown). 2019 Oct 1;17(4):376-381. doi: 10.1093\/ons\/opz013.<\/p>\n\n\n\n

Alkins R, Huang Y, Pajek D, Hynynen K. Cavitation-based third ventriculostomy using MRI-guided focused ultrasound<\/strong><\/a>. J Neurosurg. 2013 Dec;119(6):1520-9<\/p>\n\n\n\n

Click<\/strong> here<\/a> for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":1,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[6],"sw_disease_condition_stage":[14],"class_list":["post-3016","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-neurological"],"acf":[],"yoast_head":"\nHydrocephalus\u00a0 - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Hydrocephalus\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/hydrocephalus\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hydrocephalus\u00a0 - 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