{"id":3062,"date":"2021-12-08T13:48:00","date_gmt":"2021-12-08T13:48:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=3062"},"modified":"2026-05-13T18:56:42","modified_gmt":"2026-05-13T22:56:42","slug":"tremor-orthostatic","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/tremor-orthostatic\/","title":{"rendered":"Tremor, Orthostatic\u00a0"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with orthostatic tremor. This novel technology focuses beams of ultrasound energy precisely and accurately on targets deep in the brain without damaging surrounding normal tissue.<\/p>\n\n\n\n

How it Works<\/strong>
Where the beams converge, the ultrasound produces precise ablation (thermal destruction of tissue) enabling orthostatic tremor to be treated without surgery.<\/p>\n\n\n\n

Advantages
<\/strong>For certain patients, focused ultrasound could provide a noninvasive alternative therapy with less risk of complications \u2013 such as surgical wound healing or infection \u2013 at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

A\u00a0clinical trial<\/strong><\/a>\u00a0in Toronto, Ontario, Canada is using low intensity focused ultrasound to\u00a0impact\u00a0patients with multiple types of disorders, including many types of tremors, dystonia, epilepsy, and addictive substance abuse conditions.\u00a0\u00a0<\/p>\n\n\n\n

A\u202fclinical trial<\/strong><\/a>\u202ffor patients with orthostatic tremor\u00a0has\u00a0ceased enrollment\u00a0in Canada.\u00a0<\/p>\n\n\n\n

Regulatory Approval and Reimbursement <\/h2>\n\n\n\n

Focused ultrasound treatment for orthostatic tremor is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Chavira-Hernandez G, Fasano A.\u00a0Current Approach to Surgical Management of Tremor Disorders<\/strong><\/a>. Semin Neurol. 2026 Feb 6.\u00a0doi: 10.1055\/a-2789-0271. PMID: 41539330\u00a0<\/p>\n\n\n\n

Robert Chen, MA, MB\u00a0BChir, MSc,\u00a0Krembil\u00a0Brain Institute, University Health Network (Toronto, Canada); Modulating Dysfunctional Cerebellar Activity with Low-intensity Focused Ultrasound Stimulation for Primary Orthostatic Tremor\u202fhttps:\/\/www.prnewswire.com\/news-releases\/nord-awards-eleven-new-grants-in-eight-disease-states-for-rare-disease-research-301061911.html<\/strong><\/a><\/p>\n\n\n\n

Click <\/em><\/strong>here<\/a> for additional references from PubMed.<\/strong><\/em><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":1,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[6],"sw_disease_condition_stage":[20],"class_list":["post-3062","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-neurological"],"acf":[],"yoast_head":"\nTremor, Orthostatic\u00a0 - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn about clinical trials that are investigating the use of focused ultrasound to treat Tremor, Orthostatic\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/tremor-orthostatic\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tremor, Orthostatic\u00a0 - 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