Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with glaucoma. This innovative technology focuses beams of ultrasound energy precisely and accurately on the ciliary body in the eye without damaging surrounding normal tissue. With the Eye Tech Care<\/strong><\/a> device, the focused ultrasound produces precise coagulation of a portion of the ciliary body, which decreases the intraocular pressure by reducing the production of aqueous humor. The result is a non-incisional treatment of glaucoma. The procedure does need to be done in the operating room, as anesthesia is needed.<\/p>\n\n\n\n A second mechanism of action is found in the device made by EyeSonix<\/strong><\/a>, which treats open angle glaucoma. The focused ultrasound energy is applied at several locations around the eye, which offer a mild inflammatory trigger to the trabecular meshwork and anterior chamber angle resulting in enhanced drainage of the aqueous humor. There are currently no focused ultrasound clinical trials recruiting patients with glaucoma. <\/p>\n\n\n\n The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/strong><\/a>.<\/p>\n\n\n\n See a list of treatment sites ><\/a> Search for a treatment center or clinical trial near you.<\/a><\/strong><\/p>\n\n\n\n The Eye Tech Care device has regulatory approvals for use in Europe, the Middle East, China, Latin America (Mexico), and multiple locations in South-East Asia (Malaysia, Singapore, Thailand, Philippines, Indonesia, and Vietnam).<\/p>\n\n\n\n See a video about EyeTechCare’s UCP Treatment ><\/a><\/strong><\/p>\n\n\n\n Wang W, Wang C, Zhou Y, Yan S, Li X, Xie L.\u00a0Preliminary study on the treatment of acute angle closure glaucoma with high intensity focused ultrasound\u00a0cycloplasty<\/strong><\/a>. Sci Rep. 2025 Sep 29;15(1):33574.\u00a0doi: 10.1038\/s41598-025-18675-7. PMID: 41022980\u00a0<\/p>\n\n\n\n Ge P, Yang J, Xi JW, Sang W, Yang XX, Fu ZW, Jia J, He Y. Efficacy of ultrasound cyclo-plasty in treatment of glaucoma in Asian population<\/strong><\/a>. Int J Ophthalmol. 2025 Mar 18;18(3):549-556. doi: 10.18240\/ijo.2025.03.23. eCollection 2025. PMID: 40103949<\/p>\n\n\n\n Almobarak FA, Alrubean A, Alsarhani WK, Aljenaidel A. Ultrasound cyclo plasty in advanced glaucoma: Intermediate-term success, predictors for failure and complications<\/strong><\/a>. Eur J Ophthalmol. 2024 Nov;34(6):1949-1956. doi: 10.1177\/11206721241235430. Epub 2024 Feb 29. PMID: 38425194 <\/p>\n\n\n\n Ruixue W, Wenjun D, Le J, Fangfang F, Ning L, Xiaoya C, Suyan L. A comparative study of ultrasound cycloplasty and endoscopic cyclophotocoagulation in the treatment of secondary glaucoma<\/strong><\/a>. Sci Rep. 2023 Dec 27;13(1):23073. doi: 10.1038\/s41598-023-50157-6. PMID: 38155225 <\/p>\n\n\n\n Almobarak FA, Alrubean A, Alsarhani WK, Aljenaidel A, Osman EA. Two-Year Outcomes of Ultrasound Cyclo Plasty as a First Procedure in Glaucoma<\/strong><\/a>. Semin Ophthalmol. 2023 Jul;38(5):482-489. doi: 10.1080\/08820538.2023.2170715. Epub 2023 Feb 10. PMID: 36762779 <\/p>\n\n\n\n Bolek B, Wyl\u0119ga\u0142a A, Wyl\u0119ga\u0142a E. Ultrasound ciliary plasty in glaucoma treatment: A long-term follow-up study<\/strong><\/a>. Acta Ophthalmol. 2023 May;101(3):293-300. doi: 10.1111\/aos.15290. Epub 2022 Nov 30.<\/p>\n\n\n\n Almobarak FA, Alrubean A, Alsarhani WK, Aljenaidel A, Osman EA. Two-Year Outcomes of Ultrasound Cyclo Plasty as a First Procedure in Glaucoma<\/strong><\/a>. Semin Ophthalmol. 2023 Feb 10:1-8. doi: 10.1080\/08820538.2023.2170715.<\/p>\n\n\n\n Figus M, Palma A, Covello G, Agnifili L, Posarelli C. Ultrasound Cyclo Plasty in Patients with Open Angle Glaucoma and High Myopia<\/strong><\/a>. J Glaucoma. 2023 Feb 10. doi: 10.1097\/IJG.0000000000002185.
How it Works<\/strong>
There are a couple of ways in which focused ultrasound is being investigated to address glaucoma.<\/p>\n\n\n\n
Advantages<\/strong>
The primary options for treatment of glaucoma includes a variety of medications, trabeculoplasty or more extensive surgery that may include implantation of a foreign body into the eye.
For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications \u2013 such as surgical wound healing, infection, or implantation of foreign bodies into the eye \u2013 at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary.<\/p>\n\n\n\nClinical Trials<\/h2>\n\n\n\n
See a list of laboratory research sites ><\/a><\/strong><\/p>\n\n\n\nFind a Treatment Site<\/h2>\n\n\n\n
Regulatory Approval and Reimbursement <\/h2>\n\n\n\n
Notable Papers<\/h2>\n\n\n\n
Click <\/strong>here<\/a> for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":3,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[27],"sw_disease_condition_stage":[19,20],"class_list":["post-3146","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-ophthalmological"],"acf":[],"yoast_head":"\n