{"id":3152,"date":"2021-12-08T14:11:00","date_gmt":"2021-12-08T14:11:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=3152"},"modified":"2025-06-05T11:13:43","modified_gmt":"2025-06-05T15:13:43","slug":"macular-degeneration","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/macular-degeneration\/","title":{"rendered":"Macular Degeneration\u00a0"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with macular degeneration, and a number of other ocular diseases where microvessel accumulation is problematic. This novel technology focuses beams of ultrasound energy precisely and accurately on targets in the eye without damaging surrounding normal tissue.<\/p>\n\n\n\n

How it Works<\/strong>
Histotripsy is applied to the targeted microvessels in combination with low energy laser, resulting in the destruction of the microvessels. While significant preclinical work has been accomplished, there is still much to be done before this technology will be widely available.

Advantages<\/strong>
The primary options for treatment of macular degeneration include other combinations of medication and light, which have a higher risk for side effects.<\/p>\n\n\n\n

For certain patients, focused ultrasound could provide a noninvasive alternative to surgery with less risk of complications at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment of macular degeneration. <\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/a><\/strong>.\u00a0<\/p>\n\n\n\n

Regulatory Approval and Reimbursement <\/h2>\n\n\n\n

Focused ultrasound treatment for macular degeneration. is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Park Y, Shin J, Park J, Kim S, Park JH, Kim J, Kim CS, Chang JW, Schuurmans C, Aubert I, Chang WS, Eom K. Focused Ultrasound as a Novel Non-Invasive Method for the Delivery of Gold Nanoparticles to Retinal Ganglion Cells<\/strong><\/a>. Transl Vis Sci Technol. 2024 May 1;13(5):5. doi: 10.1167\/tvst.13.5.5. PMID: 38713474 <\/p>\n\n\n\n

Zhang H, Xie X, Li J, Qin Y, Zhang W, Cheng Q, Yuan S, Liu Q, Paulus YM, Wang X, Yang X. Removal of choroidal vasculature using concurrently appliedultrasound bursts and nanosecond laser pulses<\/strong><\/a>. Sci Rep. 2018 Aug 27;8(1):12848. doi: 10.1038\/s41598-018-31045-w.<\/p>\n\n\n\n

Click here<\/a>\u00a0for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[27],"sw_disease_condition_stage":[14],"class_list":["post-3152","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-ophthalmological"],"acf":[],"yoast_head":"\nMacular Degeneration\u00a0 - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Macular Degeneration\u00a0\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/macular-degeneration\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Macular Degeneration\u00a0 - 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