{"id":3279,"date":"2021-12-08T14:25:00","date_gmt":"2021-12-08T14:25:00","guid":{"rendered":"https:\/\/fusfoundation.org\/?post_type=sw_disease_condition&p=3279"},"modified":"2025-06-05T11:35:20","modified_gmt":"2025-06-05T15:35:20","slug":"sinonasal-disease","status":"publish","type":"sw_disease_condition","link":"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/sinonasal-disease\/","title":{"rendered":"Sinonasal Disease"},"content":{"rendered":"\n

Focused Ultrasound Therapy<\/h2>\n\n\n\n

Focused ultrasound is a noninvasive, therapeutic technology with the potential to improve the quality of life and decrease the cost of care for patients with sinonasal disease. This novel technology focuses beams of ultrasound energy precisely and accurately on targets in the nose without damaging surrounding normal tissue.<\/p>\n\n\n\n

How it Works
<\/strong>Where the beams converge, focused ultrasound produces thermal ablation of the target, which can treat turbinate hypertrophy and possibly other conditions in the nose. There are a couple of manufacturers making devices to help with this treatment.<\/p>\n\n\n\n

In a preclinical study, focused ultrasound was nearly twice as effective as radiofrequency ablation for treatment of inferior turbinate hypertrophy.<\/p>\n\n\n\n

Advantages<\/strong>
The primary options for treatment of sinonasal disease include medication, radiofrequency turbinoplasty or invasive surgery.<\/p>\n\n\n\n

For certain patients, focused ultrasound could provide an alternative to surgery with less risk of complications \u2013 such as surgical wound healing or infection \u2013 at a lower cost. It can reach the desired target without damaging surrounding tissue and is repeatable, if necessary. While significant preclinical work has been accomplished, there is still much to be done before this technology will be widely available.<\/p>\n\n\n\n

Clinical Trials<\/h2>\n\n\n\n

At the present time, there are no clinical trials recruiting patients for focused ultrasound treatment of sinonasal disease.<\/p>\n\n\n\n

The Foundation updates these pages regularly, but with the increasing number of clinical trials, we want to be sure that our audience has the latest information available. Therefore, we also added the website search information for the above trials. If you click here<\/strong><\/a>, it will take you to the latest information available from https:\/\/www.clinicaltrials.gov\/<\/a><\/strong>.<\/p>\n\n\n\n

Regulatory Approval and Reimbursement <\/h2>\n\n\n\n

Focused ultrasound treatment for sinonasal disease is not yet approved by regulatory bodies or covered by medical insurance companies.<\/p>\n\n\n\n

Notable Papers<\/h2>\n\n\n\n

Al-Halali A, Khalaf A, Yaseen E. The Effectiveness of Hight-Intensity Focused Ultrasound in Treating Nasal Obstruction Caused by Inferior Turbinate Hypertrophy: A Clinical Study<\/strong><\/a>. <\/strong>Cureus 2024 April 15. Doi:10.7759\/cureus.58348 <\/p>\n\n\n\n

Kim HG, Kim DS, Choi YS, Lee ES, Yoo HJ, Kim DY. High-intensity focused ultrasound therapy versus Coblation for treatment of inferior turbinate hypertrophy: Clinical trial<\/strong><\/a>. Clin Exp Otorhinolaryngol. 2023 Feb 13. doi: 10.21053\/ceo.2022.01312. PMID: 36791808 <\/p>\n\n\n\n

Kim JK, Cho SW, Kim H, Jo SC, Kim HG, Won TB, Kim JW, Lim JH, Rhee CS.\u202fDevelopment of High-Intensity Focused Ultrasound (HIFU) Therapy in Inferior Turbinate Hypertrophy<\/strong><\/a>. Clin Exp Otorhinolaryngol. 2021 Mar 30. doi: 10.21053\/ceo.2020.02383.\u00a0<\/p>\n\n\n\n

Click here<\/a> for additional references from PubMed.<\/strong><\/p>\n","protected":false},"template":"","meta":{"_acf_changed":false,"_searchwp_excluded":"","_editorskit_title_hidden":false,"_editorskit_reading_time":1,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"sw_disease_condition_cat":[58],"sw_disease_condition_stage":[20],"class_list":["post-3279","sw_disease_condition","type-sw_disease_condition","status-publish","hentry","sw_disease_condition_cat-respiratory"],"acf":[],"yoast_head":"\nSinonasal Disease - Focused Ultrasound Foundation<\/title>\n<meta name=\"description\" content=\"Learn how focused ultrasound, a noninvasive therapeutic technology, is being investigated to address Sinonasal Disease\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fusfoundation.org\/diseases-and-conditions\/sinonasal-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Sinonasal Disease - 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