{"id":539,"date":"2022-03-24T17:07:39","date_gmt":"2022-03-24T17:07:39","guid":{"rendered":"https:\/\/fusfoundation.org\/the-technology\/intellectual-property\/"},"modified":"2026-05-12T12:04:08","modified_gmt":"2026-05-12T16:04:08","slug":"intellectual-property","status":"publish","type":"page","link":"https:\/\/www.fusfoundation.org\/the-technology\/intellectual-property\/","title":{"rendered":"Intellectual Property"},"content":{"rendered":"\n

Starting in 2020, the Foundation began tracking all new focused ultrasound patents issued by the US Patent Office.  This page is updated on a quarterly basis.<\/p>\n\n\n\n

For companies seeking intellectual property advice, we have also provided a curated a list of IP\/regulatory lawyers<\/a>.<\/p>\n\n\n\n

January 1, 2020 \u2013 March 31, 2026<\/h2>\n\n\n\n

Patents Issued <\/strong><\/h3>\n\n\n\n

Patent Number:<\/strong> US12589261
Patent Title:<\/strong> Histotripsy Systems and Methods
Patent Owner:<\/strong> HistoSonics, Inc.
Date Issued: <\/strong>March 31, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12582847
Patent Title:<\/strong> Bronchial Denervation Using Integrated A-mode Signal for Optimization of Ultrasound Treatment
Patent Owner:<\/strong> AerWave Medical, Inc.
Date Issued: <\/strong>March 24, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12582848
Patent Title:<\/strong> Minimally Invasive Histotripsy Systems and Methods
Patent Owner:<\/strong> The Regents of the University of Michigan
Date Issued: <\/strong>March 24, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12564735
Patent Title:<\/strong> Systems and Methods for Modulation and Mapping of Brain Tissue Using an Ultrasound Assembly
Patent Owner:<\/strong> The Trustees of Columbia University in the City of New York
Date Issued: <\/strong>March 3, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12564738
Patent Title:<\/strong> Temperature Measurement-Based High-Intensity Focused Ultrasound Output Device
Patent Owner:<\/strong> SKINGRAB CO., LTD. (Korea)
Date Issued: <\/strong>March 3, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12558574
Patent Title:<\/strong> Method and System for Parameterising a High-Intensity Focused Ultrasound Treatment Device
Patent Owner:<\/strong> Commissariat \u00e0 l’\u00e9nergie atomique et aux \u00e9nergies alternatives; EDAP-TMS
Date Issued: <\/strong>February 24, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12551222
Patent Title:<\/strong> Operator-Independent Histotripsy Device
Patent Owner:<\/strong> Quantanosis AI, Inc.
Date Issued: <\/strong>February 17, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12544599
Patent Title:<\/strong> Leakage-Preventing Coupling Structure of Transducer Array of High-Intensity Focused Ultrasound Generator, and Transducer Array
Patent Owner:<\/strong> JEISYS MEDICAL INC. (Korea)
Date Issued: <\/strong>February 10, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12534765
Patent Title:<\/strong> Methods and Systems for Noninvasive and Localized Brain Liquid Biopsy Using Focused Ultrasound
Patent Owner:<\/strong> Washington University
Date Issued: <\/strong>January 27, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12533531
Patent Title:<\/strong> Treating Bleeding and Bleeding Disorders via High Intensity Focused Ultrasound Stimulation of the Spleen
Patent Owner:<\/strong> The Feinstein Institutes for Medical Research
Date Issued: <\/strong>January 27, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12533533
Patent Title:<\/strong> Sealing Components, Focused Ultrasound Treatment System and Operation Method, Semi-Dry Acoustic Coupling Apparatus
Patent Owner:<\/strong> Hangzhou Fosurg Technology Co., Ltd. (China)
Date Issued: <\/strong>January 27, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12527976
Patent Title:<\/strong> Histotripsy Acoustic and Patient Coupling Systems and Methods
Patent Owner:<\/strong> HistoSonics, Inc.
Date Issued: <\/strong>January 20, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12521574
Patent Title:<\/strong> Systems and Methods for Enhancing Efficacy of Ultrasound Treatment
Patent Owner:<\/strong> Ulthera, Inc.
Date Issued: <\/strong>January 13, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12514661
Patent Title:<\/strong> Robotic Platform to Navigate MRI-Guided Focused Ultrasound System
Patent Owner:<\/strong> The University of Hong Kong
Date Issued: <\/strong>January 6, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12515079
Patent Title:<\/strong> Systems and Methods for Personalized Ultrasound Neuromodulation
Patent Owner:<\/strong> Carnegie Mellon University
Date Issued: <\/strong>January 6, 2026<\/p>\n\n\n\n

Patent Number:<\/strong> US12502561
Patent Title:<\/strong> 4th Generation Linear-focused-type High-intensity Focused Ultrasound System
Patent Owner:<\/strong> WEVER INSTRUMENTS CO., LTD
Date Issued: <\/strong>December 23, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> <\/strong>US12502560
Patent Title:<\/strong> <\/strong>Cartridge For High Intensity Focused Ultrasound Generator Apparatus and Apparatus Including the Same
Patent Owner:<\/strong> <\/strong>LUTRONIC CORPORATION
Date Issued: <\/strong><\/strong>December 23, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12502559
Patent Title:<\/strong> Bronchial Denervation Using Integrated A-mode Signal for Optimization of Ultrasound Treatment
Patent Owner:<\/strong> AerWave Medical, Inc.
Date Issued: <\/strong>December 23, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12502558
Patent Title:<\/strong> Trans-skull Focused Ultrasound Using Acoustic Hologram and Heterogenous Angular Spectrum Approach, and Hologram Registration
Patent Owner:<\/strong> Georgia Tech Research Corporation
Date Issued: <\/strong>December 23, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12496466
Patent Title:<\/strong> Simulation-based Drug Treatment Planning
Patent Owner:<\/strong> Insightec Ltd.
Date Issued: <\/strong>December 16, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12496082
Patent Title:<\/strong> Multi-focal Shockwave Output Handle Unit for Extracorporeal Shockwave Therapy Device Using Multi-Piezoelectric Configuration
Patent Owner:<\/strong> K1MED GLOBAL INC.
Date Issued: <\/strong>December 16, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12491384
Patent Title:<\/strong> Histotripsy Systems and Methods
Patent Owner:<\/strong> HistoSonics, Inc.
Date Issued: <\/strong>December 9, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12491383
Patent Title:<\/strong> Generating Histotripsy Therapy Pulses Using Full Cycle Transmit
Patent Owner:<\/strong> Acoustiic INC.
Date Issued: <\/strong>December 9, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12491382
Patent Title:<\/strong> Histotripsy Systems and Methods
Patent Owner:<\/strong> HistoSonics, Inc.
Date Issued: <\/strong>December 9, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12472387
Patent Title:<\/strong> Accelerating Cutaneous Healing Utilizing Non-invasive Focused Ultrasound
Patent Owner:<\/strong> GE Precision Healthcare LLC
Date Issued: <\/strong>November 18, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12467932
Patent Title:<\/strong> Methods Of Improving Neurodegenerative Disorders by Targeted Delivery of Therapeutic Agents
Patent Owner:<\/strong> West Virginia University Board of Governors on behalf of West Virginia University
Date Issued: <\/strong>November 11, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12458381
Patent Title:<\/strong> Apparatus For Destroying Biological Tissue and Method for Trapping Biological Tissue in Fluids Flow Using the Same
Patent Owner:<\/strong> University-Industry Cooperation Group of Kyung Hee University
Date Issued: <\/strong>November 4, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12453858
Patent Title:<\/strong> Neuromodulatory Methods For Improving Addiction Using Multi-dimensional Feedback
Patent Owner:<\/strong> West Virginia University Board of Governors on Behalf of West Virginia University
Date Issued: <\/strong>October 28, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12420118
Patent Title:<\/strong> Histotripsy Systems and Methods
Patent Owner:<\/strong> HistoSonics, Inc.
Date Issued: <\/strong>September 23, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12420119
Patent Title:<\/strong> Structure Of Surgical Device For Irradiating Focused Ultrasound To Multiple Depths And Surgical Method Using The Same
Patent Owner:<\/strong> Shenb Co., Ltd. (Korea)
Date Issued: <\/strong>September 23, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12390665
Patent Title:<\/strong> Histotripsy Systems and Methods
Patent Owner:<\/strong> HistoSonics, Inc.
Date Issued: <\/strong>August 19, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12383768
Patent Title:<\/strong> Image Guided Focused Ultrasound Treatment Device And Aiming Apparatus
Patent Owner:<\/strong> FUS MOBILE INC.
Date Issued: <\/strong>August 12, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12376824
Patent Title:<\/strong> Methods, Systems, And Computer Readable Media For Utilizing A Therapeutic Ultrasound Device To Perform Mitral Valve Decalcification
Patent Owner:<\/strong> University of Virginia Patent Foundation
Date Issued: <\/strong>August 5, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12370383
Patent Title:<\/strong> Neuromodulation To Treat Physiological Conditions
Patent Owner:<\/strong> General Electric Company & Albany Medical College
Date Issued: <\/strong>July 29, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12366583
Patent Title:<\/strong> Methods Of Improving Neurodegenerative Disorders By Targeted Delivery Of Therapeutic Agents
Patent Owner:<\/strong> West Virginia University Board of Governors on behalf of West Virginia University
Date Issued: <\/strong>July 22, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12350525
Patent Title:<\/strong> Histotripsy Using Very Short Ultrasound Pulses
Patent Owner:<\/strong> The Regents of the University of Michigan
Date Issued: <\/strong>July 8, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> 12343568
Patent Title:<\/strong> Ultrasound Transducer With Transmit-receive Capability For Histotripsy
Patent Owner:<\/strong> The Regents of the University of Michigan
Date Issued: <\/strong>July 1, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12329433
Patent Title:<\/strong> Systems, Devices, and Methods for Treatment of Nasal Disorders
Patent Owner:<\/strong> Arrinex, Inc
Date Issued: <\/strong>June 17, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12329991
Patent Title:<\/strong> Wearable Transcranial Dual-mode Ultrasound Transducers For Neuromodulation
Patent Owner:<\/strong> University of Minnesota System
Date Issued: <\/strong>June 17, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12318637
Patent Title:<\/strong> Systems And Methods For Reducing Thermal Skull-induced Aberrations During Transcranial Ultrasound Therapeutic Procedures
Patent Owner:<\/strong> Sunnybrook Research Institute
Date Issued: <\/strong>June 3, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12318636
Patent Title:<\/strong> Histotripsy Systems and Methods
Patent Owner:<\/strong> Histosonics, Inc
Date Issued: <\/strong>June 3, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12310697
Patent Title:<\/strong> Methods And Systems For Noninvasive And Localized Brain Liquid Biopsy Using Focused Ultrasound
Patent Owner:<\/strong> Washington University in St Louis (WUSTL)
Date Issued: <\/strong>May 27, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12274496
Patent Title:<\/strong> Methods For Photoacoustic Temperature Measurement
Patent Owner:<\/strong> Bin Rao (Individual)
Date Issued: <\/strong>April 15, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12251451
Patent Title:<\/strong> Emulsion For Ultrasound Ablation Surgery
Patent Owner:<\/strong> Avignon Universit\u00e9, Centre National De La Recherche Scientifique\u2014CNRS, Institut National De La Sant\u00e9 Et De La Recherche M\u00e9dicale, Sorbonne Universit\u00e9, Universite De Montpellier, Ecole Nationale Superieure Se Chimie De Montpellier
Date Issued: <\/strong>March 18, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12251583
Patent Title:<\/strong> Cavitation Based Tissue Removal Device Using Focused Ultrasound
Patent Owner<\/strong>: Korea Institute of Science ad Technology
Date Issued: <\/strong>March 18, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12233288
Patent Title:<\/strong> Motion Based Methods For Cosmetic Ultrasound Treatments
Patent Owner:<\/strong> Venusa Group LLC
Date Issued: <\/strong>February 25, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12220602
Patent Title:<\/strong> Histotripsy Therapy Systems And Methods For The Treatment Of Brain Tissue
Patent Owner:<\/strong> The Regents of the University of Michigan
Date Issued: <\/strong>February 11, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12220603
Patent Title:<\/strong> High-intensity Focused Ultrasound Apparatus And Control Method
Patent Owner:<\/strong> Ultrasound Assisted Medtech PTE. LTD. (China)
Date Issued: <\/strong>February 11, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12207930
Patent Title:<\/strong> Non-invasive Transcranial Stimulation System And Method Using Pre-recorded Neurostimulation Data
Patent Owner:<\/strong> Xerox Corporation
Date Issued: <\/strong>January 28, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US12186594
Patent Title:<\/strong> Pulsed Focused Ultrasound Therapy For Treatment Of Pancreatic Disorders
Patent Owner:<\/strong> The Board of Trustees of the Leland Stanford Junior University
Date Issued: <\/strong>January 7, 2025<\/p>\n\n\n\n

Patent Number:<\/strong> US 12168055 B2
Patent Title: <\/strong>Sonosensitization
Patent Owner:<\/strong> SonalaSense, Inc.
Date Issued: <\/strong>December 17, 2024<\/p>\n\n\n\n

Patent Number: <\/strong>US 12133728 B2
Patent Title:<\/strong> Systems And Methods For Evaluating Tissue Of A Subject
Patent Owner:<\/strong> UNIVERSITY OF WASHINGTON FRED HUTCHINSON CANCER RESEARCH CENTER
Date Issued:<\/strong> November 5, 2024<\/p>\n\n\n\n

Patent Number: <\/strong>US 12133994 B2
Patent Title: <\/strong>Focused Ultrasound Device And Image Transducer Protection Method
Patent Owner: <\/strong>IMGT CO., LTD.
Date Issued: <\/strong>November 5, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> US 12127887 B2
Patent Title:<\/strong> Method For Obtaining Elastic Properties Of A Soft Solid, Which Uses Acoustic Vortices
Patent Owner:<\/strong> CONSEJO SUPERIOR DE INVESTIGACIONES CIENT\u00cdFICAS UNIVERSITAT POLIT\u00c9CNICA DE VAL\u00c9NCIA
Date Issued: <\/strong>October 29, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> US 12127979 B2
Patent Title:<\/strong> Robotic Cataract Surgery Using Focused Ultrasound
Patent Owner: <\/strong>Johnson & Johnson Surgical Vision, Inc.
Date Issued: <\/strong>October 29, 2024<\/p>\n\n\n\n

Patent Number: <\/strong>12096980
Patent Title:<\/strong> Mediator-free universal laser light amplification with coaxial propagating focused ultrasound and system
Patent Owner: <\/strong>Phononz Inc
Date Issued:<\/strong> September 24, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> 12090347
Patent Title:<\/strong> High intensity focused ultrasonic device with vertical assembly structure
Patent Owner:<\/strong> Ecleo Co., Ltd.
Date Issued:<\/strong> September 17, 2024<\/p>\n\n\n\n

Patent Number: <\/strong>12064649
Patent Title: <\/strong>Ultrasound probe for treating external body tissues
Patent Owner:<\/strong> Biotec Italia S.R.L.
Date Issued: <\/strong>August 20, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> 12059583
Patent Title:<\/strong> Ultrasonic transducer and focused ultrasound treatment device
Patent Owner:<\/strong> Chongqing Haifu Medical Technology Co., Ltd.
Date Issued:<\/strong> August 13, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> 12053198
Patent Title:<\/strong> Apparatus and method for precise mechanical tissue ablation using pressure modulated focused ultrasound
Patent Owner:<\/strong> Korea Institute Of Science And Technology
Date Issued:<\/strong> August 6, 2024<\/p>\n\n\n\n

Patent Number: <\/strong>12053653
Patent Title:<\/strong> Focused ultrasound device and method for setting order of focused ultrasound treatment thereof
Patent Owner:<\/strong> IMGT Co., Ltd.
Date Issued: <\/strong>August 6, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> 12054788
Patent Title:<\/strong> Methods and systems for noninvasive and localized brain liquid biopsy using focused ultrasound
Patent Owner:<\/strong> Washington University
Date Issued: August 6, 2024<\/p>\n\n\n\n

Patent Number:<\/strong> 12023055
Patent Title:<\/strong> Balloon catheter system assisted by ultrasound and microbubbles and method for vasodilation
Patent Owner:<\/strong> National Tsing Hua University
Date Issued:<\/strong> July 2, 2024<\/p>\n\n\n\n

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