{"id":5523,"date":"2022-04-26T11:59:11","date_gmt":"2022-04-26T15:59:11","guid":{"rendered":"https:\/\/fusfoundation.org\/?page_id=5523"},"modified":"2025-03-18T17:18:29","modified_gmt":"2025-03-18T21:18:29","slug":"open-science-policy-funded-research","status":"publish","type":"page","link":"https:\/\/www.fusfoundation.org\/for-researchers-and-clinicians\/open-science-policy-funded-research\/","title":{"rendered":"Open Science Policy for Funded Research"},"content":{"rendered":"\n

Research must be conducted transparently and held to a high standard of scientific integrity. Furthermore, it is imperative that \u2013 once conducted \u2013 the results of research are shared as widely and quickly as possible. This both ensures that important developments in focused ultrasound technology are accessible to the public and optimizes the information and resources available to researchers investigating its potential applications. Our policies reflect our commitment to these principles and are designed to ensure the transparency and accessibility of the research we fund.
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Current Requirements<\/h2>\n\n\n\n

Open Publication
<\/strong>The Foundation requires that all research resulting from Foundation awards be made publicly and freely available \u2013 this means publishing in an open-access journal. The Foundation will reimburse awardees for the direct additional costs associated with selecting a journal\u2019s open-access publication option.<\/p>\n\n\n\n

Depositing Preprints<\/strong>
The Foundation requires all awardees deposit a copy of their final report in our preprint server for publication. Our server, FocUS Archive<\/a>, is hosted by the Center for Open Science (COS) and publicly indexed by way of Crossref<\/a> \u2013 the purpose of this server is to ensure that final reports of Foundation-funded research are available as quickly and broadly as possible.<\/p>\n\n\n\n

Data Availability Statements<\/strong>
All research funded directly by the Foundation is required to be published with a data availability statement that specifies how data generated will be archived or made available to other researchers. Learn More About this Policy. <\/a><\/p>\n\n\n\n

Depositing Data in Public Repositories<\/strong>
The Foundation reserves the right to ask awardees to deposit their study data in public repositories \u2013 or to allow the Foundation to do so itself. We will discuss whether this requirement applies to a given project with the awardee during the contracting process; currently, we see this requirement most commonly in brain and oncology studies. In the specific case of immuno-oncology research<\/a>, the Foundation asks awardees to deposit their data in the immuno-oncology repository we co-founded with COS<\/a>.  

Clinical Trial Preregistration<\/strong>
Clinical trials must be prospectively registered in accordance with FDA regulations and field standards on clinicaltrials.gov.
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Expectations and Future Requirements<\/h2>\n\n\n\n

Open Data, Code, and Materials<\/h3>\n\n\n\n

Transparency<\/strong>
The policy of the Foundation is to fund proposals in which the data, analytical methods (code), and materials used to conduct the research are clearly and precisely documented and maximally available to any researcher for purposes of reproducing the results or replicating the procedure. Completion of this requirement should be documented in the final progress report. Furthermore, awardees should include availability statements for code and materials in their publication indicating whether these aspects of their research are publicly available and, if so, where.<\/p>\n\n\n\n

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  1. Awardees reusing data already available from public repositories should provide program code, scripts for statistical packages, and other documentation sufficient to allow an informed researcher to precisely reproduce all reported results.<\/li>\n\n\n\n
  2. Awardees producing their own data are strongly encouraged to:\n
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    1. Make the data available at a trusted digital repository (Note: if all data required to reproduce reported analyses appears in the article text, tables, and figures then it does not also need to be posted to a repository).\n
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      1. As noted above: in certain instances, the Foundation will require awardees to deposit their data in certain data repositories.<\/li>\n\n\n\n
      2. In all other instances, the Foundation reserves the right to ask awardees to deposit data in certain data repositories.<\/li>\n<\/ol>\n<\/li>\n\n\n\n
      3. Include all variables, treatment conditions, and observations described in the manuscript.<\/li>\n\n\n\n
      4. Provide a full account of the procedures used to collect, preprocess, clean, or generate the data.<\/li>\n\n\n\n
      5. Provide program code, scripts, codebooks, and other documentation sufficient to precisely reproduce all published results.<\/li>\n\n\n\n
      6. Provide research materials and description of procedures necessary to conduct an independent replication of the research.<\/li>\n\n\n\n
      7. Provide detailed descriptions of the treatment parameters for any focused ultrasound studies. See detailed reporting instructions<\/a>; awardees are expected to observe all relevant requirements and recommendations noted therein.<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n\n\n\n

        Data Repositories<\/strong>
        The Foundation encourages depositing research data in a public repository. We recommend researchers upload their data to the         Focused Ultrasound Collection on the Open Science Framework<\/a>. Find instructions for doing so here<\/a>. We also support uploading to other trusted public repositories such as Figshare<\/a> or Zenodo<\/a>.<\/p>\n\n\n\n

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        Exceptions<\/strong>
        In rare cases, despite awardees\u2019 best efforts, some or all data or materials cannot be shared for legal or ethical reasons. In such cases, researchers should include an explanation and justification for the non-disclosure of any data or materials. Although the awardee may provide other rationale, most appeals fall into the following three categories:<\/p>\n\n\n\n

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        1. Human Subject Grounds: Human subject\u2019s protection requires removing identifiers, which may be prohibitively expensive or render the data meaningless in research that relies heavily on personal interviews. Data sharing may not violate privacy regulations stipulated by HIPAA or fail in any way to safeguard the rights of research participants. It is the responsibility of the applicant to make a case for why the use of the HIPAA Safe Harbor de-identification method would not be feasible for their data.<\/li>\n\n\n\n
        2. Superseding Regulations Grounds: Governing laws or institutional policies limit the release of certain data.<\/li>\n\n\n\n
        3. Intellectual Property (IP) Grounds: Temporary suspension of data release until IP rights have been legally established.<\/li>\n<\/ol>\n\n\n\n

          Citation<\/strong>
          The Foundation expects that all data, program code, and other methods will be appropriately cited. Such materials are recognized as original intellectual contributions and afforded recognition through citation.<\/p>\n\n\n\n

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          1. All data sets and program code used in a report or publication generated by this funding should be cited in the text and listed in the reference section.<\/li>\n\n\n\n
          2. References for data sets and program code should include a persistent identifier, such as a Digital Object Identifier (DOI). Persistent identifiers are assigned to data sets by digital archives, such as institutional repositories, and ensure future access to unique published digital objects.<\/li>\n\n\n\n
          3. When citing any research product, awardees should include the DOI and Object type (preprints, datasets, program codes) in the citation. Awardees should also list any information about the document version (e.g. date of last modification) as well as the date the product was cited if relevant. Included below are examples of preferred citation formats for preprints and datasets provided by the National Institutes of Health (NIH). More information available at this address<\/a> regarding acceptable variations of these citation formats and examples of other citation formats).\n
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            1. Preprint<\/strong> ex: Bar DZ, Atkatsh K, Tavarez U, Erdos MR, Gruenbaum Y, Collins FS. Biotinylation by antibody recognition- A novel method for proximity labeling. BioRxiv 069187 [Preprint]. August 11, 2016 [cited 2017 Jan 12]. Available from: https:\/\/doi.org\/10.1101\/069187<\/a><\/li>\n\n\n\n
            2. Dataset ex:<\/strong> Kraemer MUG, Sinka ME, Duda KA, Mylne A, Shearer FM,\u202fBrady OJ, Messina JP, Barker CM, Moore CG, Carvalho RG, Coelho GE, Van Bortel W, Hendrickx G, Schaffner F, Wint GRW, Elyazar IRF, Teng H, Hay SI.\u202fThe global compendium of Aedes aegypti and Ae. albopictus occurrence [dataset]. 2015 Jun 30 [cited 2015 Oct 23]. Dryad Digital Repository. Available from:\u202fhttps:\/\/datadryad.org\/resource\/doi<\/a>:10.5061\/dryad.47v3c\u202fReferenced in doi: 10.7554\/eLife.08347<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n\n\n\n

              Design and Analysis Transparency <\/h3>\n\n\n\n

              The Foundation expects that all research it funds will conform to high standards of design and analysis transparency. Awardees should review the standards available here<\/a> and use those that are relevant for their reported research applications. Awardees should note which standards they plan to conform to in their proposal and demonstrate conformity in the manuscript.
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              Encouraged Actions <\/h2>\n\n\n\n

              Registered Reports<\/h3>\n\n\n\n

              The Foundation accepts and encourages applications to conduct research in the Registered Report format<\/a>. Registered Reports differ from traditional publishing formats in that the research question and proposed methodology undergo peer review before data collection ever takes place. Furthermore, the results of all data collection and analysis that do take place are published regardless of content \u2013 this means that researchers are guaranteed publication of well-conducted research and are thus free to accurately report serendipitous findings or data that does not support their initial hypothesis. Research proposals that include a plan for submitting work as a Registered Report will receive favor.

              Regarding the altered publication process and timeline of a Registered Report:<\/p>\n\n\n\n